Monoclonal
antibody services
ProSci offers custom monoclonal antibody development services using hybridoma development technology through comprehensive packages to fulfill your antibody needs. We understand researchers have a wide array of needs and levels of involvement in developing monoclonal antibodies depending on your target. With our flexible services, broad range of antibody development expertise, and enhanced capabilities, we meet your antibody success needs and provide custom monoclonal antibody solutions.
Premier
Client-Provided Antigen
Starting Price: $5,860
Time: ~18-25 weeks
12-16 weeks
Phase I: Immunization
- 3 BALB/c mice
- 1 Pre-immune serum collection
- 5 Immunizations
- 4 Serum collections
- ELISA testing of serum
2-3 weeks
Phase II: Fusion
- Fusion of 1 mouse spleen
- ELISA screening
4-6 weeks
Phase III: Subcloning
- 2 subcloning steps
- Final clone isotyping
Deliverables
- ELISA data
- Supernatant for testing (optional)
- 1 ELISA-positive clone
Pro
Client-Provided Antigen
Starting Price: $9,675
Time: ~18-25 weeks
12-16 weeks
Phase I: Immunization
- 5 BALB/c mice
- 1 Pre-immune serum collection
- 5 Immunizations
- 4 Serum collections
- ELISA testing of serum
2-3 weeks
Phase II: Fusion
- Fusion of 1 mouse spleen
- ELISA screening
4-6 weeks
Phase III: Subcloning
- 2 subcloning steps
- Final clone isotyping
Deliverables
- ELISA data
- Supernatant for testing (optional)
- 3 ELISA-positive clones
Plus
ProSci-Provided Antigen
Starting Price: $11,010
Time: ~22-30 weeks
4-5 weeks
Antigen Design & Synthesis
- Antigen design
- Peptide synthesis of up to 25 aa at >90% purity
- Conjugation to carrier protein
12-16 weeks
Phase I: Immunization
- 5 BALB/c mice
- 1 Pre-immune serum collection
- 5 Immunizations
- 4 Serum collections
- ELISA testing of serum
2-3 weeks
Phase II: Fusion
- Fusion of 1 mouse spleen
- ELISA screening
4-6 weeks
Phase III: Subcloning
- 2 subcloning steps
- Final clone isotyping
Deliverables
- ELISA data
- Supernatant for testing (optional)
- 3 ELISA-positive clones
Package Add-ons
- Additional ELISA Screening
- Additional Final Clones
- Final Clone Isotyping
- In vitro production
- Endotoxin testing and removal
- Antibody Sequencing
- Affinity Measurement
- Flow Cytometry Validation