Polyclonal
antibody services

ProSci's polyclonal antibodies are available in a wide variety of custom configurations and standard packages to optimize research experience. A polyclonal antibody from ProSci is flexible, reliable and easy to use which enables good results for any experiment. Outsourcing standard or custom polyclonal antibody development to ProSci's antibody experts allows researchers to focus on optimizing other aspects of experiments that require more attention.

Serum

Client-Provided Antigen

Starting Price: $1,815

Time: ~13 weeks

13 weeks
Immunization Protocol
  • 1 Sheep
  • 1 Pre-immune serum collection
  • 4 Immunizations per sheep
  • 4 Production serum collections per sheep
Deliverables
  • Pre-immune serum, ~25 ml each sheep
  • 4 Production serum collections, ~150-250 ml each sheep

Peptide

ProSci-Provided Antigen

Starting Price: $2,510

Time: ~15-16 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
13 weeks
Immunization Protocol
  • 1 Sheep
  • 1 Pre-immune serum collection
  • 4 Immunizations per sheep
  • 4 Production serum collections per sheep
Deliverables
  • Pre-immune serum, ~25 ml each sheep
  • 4 Production serum collections, ~150-250 ml each sheep
  • 5 mg peptide
  • ELISA report

Purified

ProSci-Provided Antigen + Serum
Purification

Starting Price: $3,145

Time: ~16-17 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
13 weeks
Immunization Protocol
  • 1 Sheep
  • 1 Pre-immune serum collection
  • 4 Immunizations per sheep
  • 4 Production serum collections per sheep
1-2 weeks
Purification
  • Immuno-affinity purification of 25 ml
    serum against peptide
Deliverables
  • Pre-immune serum, ~25 ml each sheep
  • 4 Production serum collections, ~150-250 ml each sheep
  • 5 mg peptide
  • ELISA report
  • Purified antibody
  • Immuno-affinity column
  • Purification report

IgY

Client-Provided Antigen

Starting Price: $855

Time: ~8 weeks

~8 weeks
Immunization Protocol
  • 2 Chickens
  • Pre-immune IgY purification
  • 4 Immunizations per chicken
  • 3 Test serum collections per chicken
  • IgY purification of eggs collected week 3-7
Deliverables
  • Project schedule
  • 5 mg pre-immune IgY
  • 3 test serum samples, ~1 ml each chicken
  • ~1000 mg immune IgY

Peptide

ProSci Provided Antigen

Starting Price: $1,635

Time: ~10-11 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 2 Chickens
  • Pre-immune IgY purification
  • 4 Immunizations per chicken
  • 3 test serum collections per chicken
  • IgY purification of eggs collected week 3-7
Deliverables
  • Project schedule
  • 5 mg pre-immune IgY
  • 2 test sera samples, ~1 ml each chicken
  • ~1000 mg immune IgY
  • 5 mg peptide
  • ELISA report

Purified

ProSci-Provided Antigen + Yolk
Purification

Starting Price: $2,475

Time: ~11-12 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 2 chickens
  • Pre-immune IgY purification
  • 4 immunizations per chicken
  • 3 test serum collections per chicken
  • IgY purification of eggs collected weeks 3-7
1-2 weeks
Immuno-Affinity Purification
  • Immuno-affinity purification of 25 mg IgY against peptide
Deliverables
  • Project schedule
  • Pre-immune serum, ~1 ml each chicken
  • 3 Test sera samples, ~1 ml each chicken
  • ~12 Yolks on average
  • 5 mg peptide
  • ELISA report
  • Purified antibody
  • Immuno-affinity column
  • Purification report

Serum

Client-Provided Antigen

Starting Price: $1,595

Time: ~8 weeks

8 weeks
Immunization Protocol
  • 5 Mice
  • 1 Pre-immune serum collection
  • 4 Immunizations per mouse
  • 1 Test serum collection
  • 1 Production serum collection
Deliverables
  • Pre-immune serum, ~0.05 ml each mouse
  • Test serum, ~0.05 ml each mouse
  • Production serum collection, ~0.5ml each mouse

Peptide

ProSci-Provided Antigen

Starting Price: $2,635

Time: ~10-11 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 5 Mice
  • 1 Pre-immune serum collection
  • 4 Immunizations per mouse
  • 1 Test serum collection
  • 1 Production serum collection
Deliverables
  • Pre-immune serum, ~0.05 ml each mouse
  • Test serum, ~0.05 ml each mouse
  • Production serum collection, ~0.5ml each mouse
  • 5 mg peptide
  • ELISA report

Purified

ProSci-Provided Antigen + Serum
Purification

Starting Price: $3,195

Time: ~11-12 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 5 Mice
  • 1 Pre-immune serum collection
  • 4 Immunizations per mouse
  • 1 Test serum collection
  • 1 Production serum collection
1-2 weeks
Purification
  • Immuno-affinity purification of 25 ml
    serum against peptide
Deliverables
  • Pre-immune serum, ~0.05 ml each mouse
  • Test serum, ~0.05 ml each mouse
  • Production serum collection, ~0.5ml each mouse
  • 5 mg peptide
  • ELISA report
  • Purified antibody
  • Immuno-affinity column
  • Purification report

Serum

Client-Provided Antigen

Starting Price: $995

Time: ~8 weeks

8 weeks
Immunization Protocol
  • 2 Rabbits
  • 1 Pre-immune serum collection
  • 4 Immunizations per rabbit
  • 3 Serum collections per rabbit
Deliverables
  • Pre-immune serum ~ 5ml each rabbit
  • 4 immunizations
  • Test serum ~ 5ml each rabbit
  • 2 Production sera ~ 10-25 mls each rabbit

Peptide

ProSci-Provided Antigen

Starting Price: $1,785

Time: ~10-11 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen Design
  • Peptide synthesis up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 2 Rabbits
  • 1 Pre-immune serum collection
  • 4 Immunizations per rabbit
  • 3 Serum collections per rabbit
  • ELISA on 1st bleed
Deliverables
  • Pre-immune serum, ~5 ml each rabbit
  • Test serum, ~5 ml each rabbit
  • Production serum, 10~20 ml each rabbit
  • Final serum, ~60 ml each rabbit
  • 5 mg peptide
  • ELISA report

Purified

ProSci-Provided Antigen + Serum
Purification

Starting Price: $2,350

Time: ~11-12 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis up to 15 aa
  • Conjugation to carrier protein
8 weeks
Immunization Protocol
  • 2 Rabbits
  • 1 Pre-immune serum collection
  • 4 Immunizations per rabbit
  • 3 Serum collections per rabbit
  • ELISA on 1st bleed
1-2 weeks
Purification
  • Immuno-affinity purification of 25 ml
    serum against peptide
Deliverables
  • Pre-immune serum, ~5 ml each rabbit
  • Test serum, ~5 ml each rabbit
  • Production serum, 10~20 ml each rabbit
  • Final serum, ~60 ml each rabbit
  • 5 mg peptide
  • ELISA report
  • Purified antibody
  • Immuno-affinity column
  • Purification report

Serum

Client-Provided Antigen

Starting Price: $1,815

Time: ~13 weeks

13 weeks
Immunization Protocol
  • 1 Goat
  • 1 Pre-immune serum collection
  • 4 Immunizations per goat
  • 4 Production serum collections per goat
Deliverables
  • Pre-immune serum, ~25 ml each goat
  • 4 Production serum collections, ~150-250 ml each goat

Peptide

ProSci-Provided Antigen

Starting Price: $2,510

Time: ~15-16 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
13 weeks
Immunization Protocol
  • 1 Goat
  • 1 Pre-immune serum collection
  • 4 Immunizations per goat
  • 4 Production serum collections per goat
Deliverables
  • Pre-immune serum, ~25 ml each goat
  • 4 Production serum collections, ~150-250 ml each goat
  • 5 mg peptide
  • ELISA report

Purified

ProSci-Provided Antigen + Serum
Purification

Starting Price: $3,145

Time: ~16-17 weeks

3-4 weeks
Antigen Design & Synthesis
  • Antigen design
  • Peptide synthesis of up to 15 aa
  • Conjugation to carrier protein
13 weeks
Immunization Protocol
  • 1 Goat
  • 1 Pre-immune serum collection
  • 4 Immunizations per goat
  • 4 Production serum collections per goat
1-2 weeks
Purification
  • Immuno-affinity purification of 25 ml
    serum against peptide
Deliverables
  • Pre-immune serum, ~25 ml each goat
  • 4 Production serum collections, ~150-250 ml each goat
  • 5 mg peptide
  • ELISA report
  • Purified antibody
  • Immuno-affinity column
  • Purification report

Serum

Client-Provided Antigen

Starting Price: $8,685

Time: ~12 weeks

12 weeks
Immunization Protocol
  • 1 Llama
  • 1 Pre-immune serum collection
  • 4 Immunizations per llama
  • 3 Production serum collections per llama
Deliverables
  • Pre-immune serum,
    ~25 ml each Llama
  • 3 Production serum collections,
    ~150-250ml each llama
Package Add-ons
  • Purify Additional Sera - Available for all Packages
  • Modification-Specific Antibodies (e.g. phospho)
  • Peptide Cocktail
  • Additional ELISAs
  • Antibody Labeling
  • Endotoxin testing and removal
  • Antibody Sequencing
  • Affinity Measurement
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Learn more in our resources:

Polyclonal InformationAntibody Development Guide