Antigens are molecules—commonly proteins or peptides—that stimulate the immune system to produce antibodies. Designing optimal antigens is a critical first step in antibody development. ProSci’s Antigen Design Services combine scientific rigor, decades of experience, and tailored engineering to deliver immunogens that reliably elicit high-quality antibody responses.
Why Antigen Design Matters
Your choice of antigen — its sequence, structure, and chemistry — underpins antibody specificity, affinity, and utility for downstream applications like western blot, immunohistochemistry, and ELISA. A suboptimal antigen may fail to provoke the immune response or generate antibodies that don’t recognize your target. Conversely, a well-optimized antigen enhances immunogenicity, boosting success rates and assay performance.
ProSci’s Expertise & Track Record
- 20+ years of antibody-focused R&D and custom antibody development.
- In-house experience designing over 20,000 custom antibodies.
- A proven 85% success rate in generating antibodies for western blot using peptide antigens.
- Over 98% immune response achieved when following ProSci’s peptide antigen designs.
These metrics underscore ProSci’s deep capacity to anticipate and address common pitfalls in immunogen design.
Benefits of Partnering with ProSci
- Expert guidance — Strategic support in selecting regions most likely to yield a strong immune response.
- Technical reliability — A peer-backed approach built upon thousands of successful projects.
- Application-focused design — Antigen choices are not one-size-fits-all. Peptides are tailored for use in western blot, IHC, IP, etc.
- Risk-free guarantee — If your initial design doesn’t prompt an immune response, ProSci re‑evaluates and resubmits peptides at no extra cost.
Who Should Use This Service?
Researchers working in basic or translational biology, diagnostics, and therapeutic antibody development can all benefit from robust antigen design. Anywhere an antibody-based assay is employed—ELISA, ICC, ICC, or even recombinant and monoclonal antibody pipelines—starting with a well-designed immunogen improves your odds of obtaining antibodies that meet experimental needs.
In Summary
Antigen design is more than a technical requirement—it’s the foundation for reliable antibody development. With ProSci’s Antigen Design Services, you gain:
- A scientifically optimized immunogen tailored for your assay
- Expertise derived from thousands of projects and a high success metric
- A customer‑centric process backed by a practical guarantee
Whether you’re launching a polyclonal, monoclonal, or recombinant antibody campaign, ProSci’s Antigen Design Services empower your project with confidence and clarity. Connect with ProSci today to begin the design of an immunogen that works as hard as you do.
